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A first-half Theo Walcott goal gave Arsenal a glimmer of hope, but Laurent Koscielny was sent off while conceding a penalty soon after the break, and Robert Lewandowski scored from the spot.
Arjen Robben, Douglas Costa then added goals before a Arturo Vidal added gloss to the scoreline with a late brace.
With the result mostly in hand after the 5-1 first leg in Germany, many Arsenal fans began their night with a pregame march khổng lồ the Emirates calling for Arsene Wenger to step down.
And after Arsenal were dealt an additional blow by losing Danny Welbeck lớn an injury in the warm-up, Bayern were comfortable in possession in the opening minutes before the Gunners found their footing.
Olivier Giroud, starting in place of Welbeck, saw the first real chance on 13 minutes, but his header from close range only scraped the outside of the post.
Walcott provided Arsenal"s goal on trăng tròn minutes after he split two defenders và blasted a shot into the roof of the net from the side of the six-yard box.
Bayern nearly erased the goal four minutes later as Vidal saw his header saved by Ospina, then put his follow-up attempt over the bar.
Arsenal continued to lớn threaten as Bayern appeared lethargic, with Walcott unfortunate not to be awarded a penalty when he was tripped by Xavi Alonso.
Bayern were able khổng lồ cruise after Laurent Koscielny was sent off.Nick Potts/PA Images via Getty ImagesWalcott had another chance from a similar position lớn where he scored hit the side netting before he was booked along with David Alaba after the two clashed.
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But as the second half began, Bayern reasserted control after Giroud headed a fine chance onto the roof of the net.
After having a goal ruled out for offside, the trò chơi ended as a contest after Koscielny was dismissed in the 53rd minute.
With Lewandowski racing in on goal, Koscielny tried lớn shoulder the striker off the ball but could not draw level và referee Tasos Sidiropoulos pointed to the spot.
Sidiropoulos originally showed the Arsenal skipper a yellow card but altered his decision and dismissed Koscielny after a conversation with the assistant referee behind the goal.
Lewandowski sent David Ospina the wrong way to lớn equalise on the night & end the round-of-16 clash as a contest.
Robben then ensured Bayern left London with the second-leg victory in the 68th minute. Ospina sent a poor clearance right khổng lồ him, và though it appeared Alexis Sanchez had won the ball back, Robben took it off his foot và scored easily.
The floodgates were opened và Costa added another goal in the 78th minute when he ran at Shkodran Mustafi before curling a shot inside the far post.
Arsenal were still attempting to lớn mount an attack two minutes later when Xabi Alonso picked off a Mustafi pass and passed ahead for Vidal to scoop a shot past the helpless Ospina.
Bayern"s fifth followed with five minutes lớn play, Renato Sanches lofting a pass over Arsenal"s high line khổng lồ Douglas Costa, who unselfishly fed across for Vidal.
